Back to category: Medical Limited version - please login or register to view the entire paper. Molecular Biology Molecular Biology - bacteria and eukaryotes are composed of double-stranded DNA - some viruses are composed of single or double stranded RNA Historical Timeline: - Meischer: discovery that DNA in nucleus - Gates: UV of 260nm kills bacteria - Avery and MacLeod : transformation of rough streptococcus to smooth using purification of nucleic acid and RNase digestion - Lederberg: accurate genetic map of E. coli based on conjugal mating - McClintock: transposable elements = jumping genes - Chargaff: hydrolyzed DNA and separated bases by paper chromatography to show base composition varied with different DNA sources - Franklin: used x-ray crystallography to discover sugar-phosphate backbone of DNA and elucidated helical structure - Hershey and Chase: differentially labeled T4 phage o Labelled protein with sulfur o Labelled DNA with phosphorous o Phosphorus detected in cell - Watson and Crick: DNA had two helical strands,... Posted by: Gelinde Cobbs Limited version - please login or register to view the entire paper. |
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