White Blood Cells

Eosinophil
Eosinophils are one of the five different types of white blood cells belonging to the subgroup called Polymorphonuclear Leukocytes. Eosinophils are produced in the bone marrow and then migrate to tissue, and they are characterized by large red cytoplasm granules. These cells have the purpose of giving large parasites such as helminths, a hard time. They attach via C3b receptors, the C3b having been produced during the course of alternative pathway complement activation by the helminth. The eosinophils release various substances from their granules. These include major basic protein plus cationic proteins, peroxidase, arylsulphatase B, phospholipase D and histaminase. The granule contents are capable of damaging the parasite membrane. Eosinophil function is incompletely understood. They are prominent at...