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UV Efficacy of Sunscreen on Yeast Cells

UV-blocking Efficacy of Sunscreen On Yeast Cells
Henry Pan
April 17, 2003

INTRODUCTION
While having a tan is still desired in this culture, people have become more aware of the dangers that prolonged ultraviolet (UV) radiation exposure presents. Problems ranging from actinic changes such as wrinkling, premature aging of the skin, and irregular thinning of the epidermis, to more serious issues like the development of premalignancies and skin cancer can result from excessive UV exposure (Campos, 2001).
UV radiation affects a cell by damaging its DNA. It promotes the formation of covalent linkage between two adjacent pyrimidine bases, resulting in thymine dimers (Alberts, 1998). This type of damage can often stall DNA replication machinery at the site of dimerization and can lead to disastrous consequences both for the cell and the organism to which it is part of. It will also interfere with the readout of genetic information and DNA replication (Goldberg, 2000).
The ...

Posted by: Darren McCutchen

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