turner's syndrome

Turner's Syndrome



H. H. Turner first described Turner syndrome in 1938. Dr. Turner observed a set of common physical features in some of his patients. Nonetheless, it was no until 1960 that a chromosomal abnormality was found. This is a genetic disorder of the chromosomes affecting females, where one of the two chromosomes is partially or completely absent. A female with Turner's syndrome has only one X chromosome in each of her cells due to a non-disjunction event during meiosis of her parents' gametes.
Normally, girls have two X chromosomes and males have one X and one Y chromosome. In Turner syndrome, an error very early in development results in an abnormal number, arrangement or damage of the chromosomes. It is common for a patient with Turner syndrome to be born with 45 chromosomes, instead of the normal 46. About one in every two thousand girls born has TS.
Intellectually, girls with Turner syndrome are not at risk for mental retardation, but may have l...