Biochemistry

Biochem. J. (2003) 371 (981-988) (Printed in Great Britain)

Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells
Juliane G. STRAUSS*, Marianne HAYN*1, Rudolt ZECHNER*, Sanja LEVAK-FRANK and Sasa FRANK 2


*Institute of Molecular Biology, Biochemistry and Microbiology, University of Graz, Heinrichstrasse 31a, Graz A-8010, Austria, and Institute of Medical Biochemistry and Medical Molecular Biology, University of Graz, Harrachgasse 21/III, Graz A-8010, Austria

Key words: adenoviral vectors, CD36, fatty acid synthase, HEK-293 cells, HepG2 cells.

Abbreviations used: CE, cholesterol ester; DAG, diacylglycerol; DMEM, Dulbecco's modified Eagle's medium; EDL, endothelial-derived lipase; EDL-Ad, EDL-expressing adenovirus; FA, fatty acids; FAS, FA synthase; FCS, fetal calf serum; HDL, high-density lipoprotein; HDL-PC, HDL-derived PC; HDL-PL, HDL-associated PL; HEK-293, human embryonic kidney ...